Description:
The combination of trimethoprim and sulfamethoxazole acts synergistic and usually bactericidal against many Gram-positive and Gram-negative bacteria like E. coli, Haemophilus, Pasteurella, Salmonella, Staphylococcus and Streptococcus spp. Both compounds affect bacterial purine synthesis in a different way, as a result of which a double blockade is accomplished.
Information
Composition:
Contains per ml:
Sulfamethoxazole …………………………………………………………………………………… 200 mg.
Trimethoprim …………………………………………………………………………………………… 40 mg.
Solvents ad ………………………………………………………………………………………………. 1 ml.
Indications:
Gastrointestinal, respiratory and urinary tract infections caused by trimethoprim and sulfamethoxazole sensitive bacteria like E. coli, Haemophilus, Pasteurella, Salmonella, Staphylococcus and Streptococcus spp. in calves, cattle, goats, sheep and swine.
Contra-indications:
Hypersensitivity to trimethoprim and/or sulfonamides.
Administration to animals with a seriously impaired renal and/or liver function or with blood dyscrasias.
Side effects:
Anaemia, leucopenia and thrombocytopenia.
Packing:
Vial of 100 ml.
Usage
Dosage:
For intramuscular administration:
General: Twice daily 1 ml per 10 – 20 kg body weight for 3 – 5 days.
Withdrawal times:
– For meat : 12 days.
– For milk : 4 days.