Description:
Piperazine is an anthelmintic with activity against nematodes. It induces a reversible flaccid paralysis in the nematode parasites. This is provoked by hyperpolarisation of the cell membrane followed by suppression of spontaneous spike potentials. The paralysed nematodes are subsequently expelled from the gut lumen by normal peristaltic actions.
Information
Composition:
Contains per gram powder:
Piperazine citrate…………………………………………………………………………….1000 mg.
Indications:
Nematode infections in horses, swine, cattle and poultry.
Horses : Strongylus, Oxyuris, Trichonema and Ascaris.
Swine : Oesophagostomum and Ascaris.
Cattle : Ascaris, Nematodirus, Ostertagia, Cooperia and Oesophagostomum.
Poultry : Ascaris and Capillaria.
Contra-indications:
Hypersensitivity to piperazine.
Administration to animals with a seriously impaired hepatic and/or renal function.
Side effects:
Overdoses can cause colic, coughing, excessive salivation, excitation, hyperpnoea, lachrymation, spasms, sweating and vomiting.
Packaging:
Sachet of 100 g and jar of 500 and 1000 g.
Usage
Dosage:
For oral administration:
Horses, swine and cattle : 1 – 2 gram g per 10 kg body weight though drinking water
Poultry : 1 kg per 1000 litres of drinking water for 2 days.
Withdrawal times:
– For meat : 2 days.
– For eggs : 2 days.
