Description
Doxycycline is a bacteriostatic agent that acts by interfering with the bacterial protein synthesis of sensitive species.
Doxycycline is a semi-synthetic tetracycline derived from oxytetracycline. It acts on the subunit 30S of the bacterial ribosome, to which it is linked reversibly, blocking the union between aminoacyl-tRNA (transfer RNA) to the mRNA-ribosome complex, preventing the addition of new aminoacids into the growing peptide chain and thus interfering with protein synthesis.
Doxycycline is active against Gram-positive and Gram-negative bacteria.
Spectrum of activity:
Streptococcus spp.
Staphylococcus aureus
Chlamydia spp.
Mycoplasma spp.
Salmonella spp.
Pasteurella multocida
Bordetella bronchiseptica
Information
Composition
Contains per ml:
Doxycycline (as hyclate) …………………………………………………………………………………100.0 mg
Solvents ad. ……………………………………………………………………………………………………..1 ml
Indications
Chickens (broilers): Prevention and treatment of chronic respiratory disease (CRD) and mycoplasmosis caused by microorganisms sensitive to doxycycline.
Pigs: Prevention of clinical respiratory disease due to Pasteurella multocida and Mycoplasma hyopneumoniae sensitive to doxycycline.
The presence of the disease in the herd should be established before treatment.
Contra indications
Do not use in case of hypersensitivity to tetracyclines.
Do not use in animals with hepatic dysfunction.
Side effects
Allergic and photosensitivity reactions can occur. Intestinal flora may be affected if treatment is very prolonged, and this may result in digestive disturbance.
Packing
Bottle containing 1000 ml
Usage
Dosage
For oral administration.
Chickens (broilers): 11.5 – 23 mg doxycycline hyclate / kg body weight / day, corresponding to 0.1 – 0.2 ml Nutridox-100 Oral per kg body weight, for 3-5 consecutive days
Pigs: 11.5 mg doxycycline hyclate/ kg body weight / day, corresponding to 0.1 ml of Nutridox-100 Oral per kg body weight, for 5 consecutive days.
Withdrawal times
– For meat & offal:
Chickens (broilers): 7 days
Pigs: 7days
-Eggs: Not permitted for use in laying birds producing eggs for human consumption.
Warning
Keep away from children.
Protect from light.
