Description:
The combination of procaine penicillin G and dihydrostreptomycin acts additive and in some cases synergistic. Procaine penicillin G is a small-spectrum penicillin with a bactericidal action against mainly Gram-positive bacteria like Clostridium, Corynebacterium, Erysipelothrix, Listeria, penicillinase negative Staphylococcus and Streptococcus spp. Dihydrostreptomycin is an aminoglycoside with a bactericidal action against mainly Gram-negative bacteria like E. coli, Campylobacter, Klebsiella, Haemophilus, Pasteurella and Salmonella spp.
Information
Composition:
Contains per ml:
Procaine penicillin G …………………………………………………………………………… 200 000 IU.
Dihydrostreptomycin sulphate …………………………………………………………………… 200 mg.
Solvents ad ………………………………………………………………………………………………. 1 ml.
Indications:
Arthritis, mastitis and gastrointestinal, respiratory and urinary tract infections caused by penicillin and dihydrostreptomycin sensitive micro-organisms, like Campylobacter, Clostridium, Corynebacterium, E. coli, Erysipelothrix, Haemophilus, Klebsiella, Listeria, Pasteurella, Salmonella, Staphylococcus and Streptococcus spp. in calves, cattle, goats, sheep and swine.
Contra-indications:
Hypersensitivity to penicillin, procaine and/or aminoglycosides.
Administration to animals with a seriously impaired renal function.
Concurrent administration of tetracyclines, chloramphenicol, macrolides and lincosamides.
Side effects:
Administration of therapeutic dosages of procaine penicillin G can result in abortion in sows.
Ototoxity, neurotoxicity or nephrotoxicity.
Hypersensitivity reactions.
Packing:
Vial of 50 and 100 ml.
Usage
Dosage:
For intramuscular administration:
Cattle : 1 ml per 20 kg body weight for 3 days.
Calves, goats, sheep and swine : 1 ml per 10 kg body weight for 3 days.
Shake well before use and do not administer more than 20 ml in cattle, more than 10 ml in swine and more than 5 ml in calves, sheep and goats per injection site.
Withdrawal times:
– For kidney : 45 days.
– For meat : 21 days.
– For milk : 3 days.
