Description:
The combination of amoxicillin and gentamicin acts synergistically against a wide range of infections caused by both Gram-positive (e.g. Staphylococcus, Streptococcus and Corynebacterium spp.) and Gram-negative (e.g. E.coli, Pasteurella, Salmonella and Pseudomonas spp.) bacteria in cattle and swine. Amoxicillin inhibits mainly in Gram-positive bacteria the cross-linkage between the linear peptidoglycan polymer chains that make up a major component of the cell wall. Gentamicin binds to the 30S subunit of the ribosome of mainly Gram-negative bacteria, thereby interrupting protein synthesis. Excretion of Gentamox occurs mainly unchanged via urine, and to a lesser degree via milk.
Information
Composition:
Contains per ml:
Amoxycillin trihydrate ……………………………………………………………………………. 150 mg.
Gentamycin base …………………………………………………………………………………… 40 mg.
Solvents ad …………………………………………………………………………………………….. 1 ml.
Indications:
Cattle: gastrointestinal, respiratory and intramammary infections caused by bacteria sensitive to the combination of amoxicillin and gentamicin, such as pneumonia, diarrhoea, bacterial enteritis, mastitis, metritis and cutaneous abscesses.
Swine: respiratory and gastrointestinal infections caused by bacteria sensitive to the combination of amoxicillin and gentamicin, such as pneumonia, colibacillosis, diarrhoea, bacterial enteritis and mastitis-metritis-agalactia syndrome (MMA).
Contra-indications:
Hypersensitivity towards amoxicillin or gentamicin.
Administration to animals with a seriously impaired liver and/or renal function.
Concurrent administration of tetracyclines, chloramphenicol, macrolides and lincosamides.
Concurrent administration of nephrotoxic compounds.
Side effects:
Hypersensitivity reactions.
Packing:
Vial of 100 ml
Usage
Dosage:
For intramuscular administration. The general dosage is 1 ml per 10 kg body weight per day for 3 days.
Cattle : 30 – 40 ml per animal per day for 3 days.
Calves : 10 – 15 ml per animal per day for 3 days.
Swine : 5 – 10 ml per animal per day for 3 days.
Piglets : 1 – 5 ml per animal per day for 3 days.
Shake well before use. Do not administer more than 20 ml in cattle or more than 10 ml in swine per injection site to favour absorption and dispersion.
Withdrawal times:
– For meat : 30 days.
– For milk : 2 days.
